Edwardsiella Tarda
Edwardsiella Tarda
MATERIAL SAFETY DATA SHEET – INFECTIOUS SUBSTANCES
SECTION I – INFECTIOUS AGENT
NAME: Edwardsiella tarda
SYNONYM OR CROSS REFERENCE: N/A
CHARACTERISTICS: Gram negative rod, facultatively anaerobic, motile with peritrichous flagella
SECTION II – HEALTH HAZARD
PATHOGENICITY: Opportunistic pathogen occasionally causing acute gastroenteritis; associated with meningitis, septicemia, and wound infections
EPIDEMIOLOGY: Worldwide
HOST RANGE: Mammals, aquatic mammals, reptiles, fish and occasionally humans
INFECTIOUS DOSE: Not known
MODE OF TRANSMISSION: Fecal-oral route; ingestion of contaminated food
INCUBATION PERIOD: Not clearly identified
COMMUNICABILITY: As long as organism is shed in feces
SECTION III – DISSEMINATION
RESERVOIR: Mammals, reptiles (intestinal tract of snakes), water (contamination from reptiles) and fish
ZOONOSIS: None
VECTORS: None
SECTION IV – VIABILITY
DRUG SUSCEPTIBILITY: Sensitive to kanamycin, ampicillin, cephalothin, ciprofloxacin, trimethroprim – sulfamethoxazole and chloramphenicol
Drug Resistance: Most strains are resistant to colistin
SUSCEPTIBILITY TO DISINFECTANTS: Susceptible to many disinfectants – l% sodium hypochlorite, 70% ethanol, 2% glutaraldehyde, iodines, phenolics, formaldehyde
PHYSICAL INACTIVATION: Sensitive to moist heat (121°C for at least 15 min) and dry heat (160-170°C for at least 1 hour)
SURVIVAL OUTSIDE HOST: Survives well in fresh water
SECTION V – MEDICAL
SURVEILLANCE: Monitor for symptoms; confirmation by stool culture
FIRST AID/TREATMENT: Administer antibiotic therapy
IMMUNIZATION: None
PROPHYLAXIS: Not usually administered
SECTION VI – LABORATORY HAZARDS
LABORATORY-ACQUIRED INFECTIONS: No reported cases to date
SOURCES/SPECIMENS: Urine, feces, blood, wound exudates
PRIMARY HAZARDS: Ingestion, accidental parenteral inoculation
SPECIAL HAZARDS: None
SECTION VII – RECOMMENDED PRECAUTIONS
CONTAINMENT REQUIREMENTS: Biosafety level 2 practices, containment equipment and facilities for activities with cultures or potentially infectious clinical materials
PROTECTIVE CLOTHING: Laboratory coat; gloves when direct contact with infectious materials is unavoidable
OTHER PRECAUTIONS: Good personal hygiene and frequent handwashing
SECTION VIII – HANDLING INFORMATION
SPILLS: Allow aerosols to settle; wearing protective clothing, gently cover spill with paper towels and apply 1% sodium hypochlorite, starting at perimeter and working towards the centre; allow sufficient contact time (30 min) before clean up
DISPOSAL: Decontaminate before disposal; steam sterilization, chemical disinfection, incineration
STORAGE: In sealed containers that are appropriately labelled
SECTION IX – MISCELLANEOUS INFORMATION
Date prepared: January, 2001
Prepared by: Office of Laboratory Security, PHAC
Although the information, opinions and recommendations contained in this Material Safety Data Sheet are compiled from sources believed to be reliable, we accept no responsibility for the accuracy, sufficiency, or reliability or for any loss or injury resulting from the use of the information. Newly discovered hazards are frequent and this information may not be completely up to date.
Copyright © Health Canada, 2001
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