Peptococcus spp.

Peptococcus spp.

MATERIAL SAFETY DATA SHEET – INFECTIOUS SUBSTANCES

SECTION I – INFECTIOUS AGENT

NAME: Peptococcus spp.

SYNONYM OR CROSS REFERENCE: P. anaerobius, P. asacharolyticus, P. constellatus, P. magnus

CHARACTERISTICS: Gram-positive cocci; anaerobic; occurs singly, in pairs or chains, or in irregular clusters; do not require fermentable carbohydrates

SECTION II – HEALTH HAZARD

PATHOGENICITY: Part of normal flora of the mouth, upper respiratory tract, large intestine and genitourinary tract; cause a variety of infections (cystitis, septic arthritis surgical wound infections), some in synergy with other organisms, infections of soft tissues and bacteremias; opportunistic organisms

EPIDEMIOLOGY: Worldwide

HOST RANGE: Humans, lower animals

INFECTIOUS DOSE: Not known

MODE OF TRANSMISSION: Most frequently associated with trauma

INCUBATION PERIOD: Not known

COMMUNICABILITY: Not transmitted from person to person

SECTION III – DISSEMINATION

RESERVOIR: Humans, animals, soil

ZOONOSIS: None

VECTORS: None

SECTION IV – VIABILITY

DRUG SUSCEPTIBILITY: Sensitive to penicillin

SUSCEPTIBILITY TO DISINFECTANTS: Susceptible to many disinfectants – 1% sodium hypochlorite, 70% ethanol, glutaraldehyde, formaldehyde, iodines

PHYSICAL INACTIVATION: Sensitive to moist heat (121·C for at least 15 min) and dry heat (160-170·C for at least 1 hour)

SURVIVAL OUTSIDE HOST: Survives well in nature ie. soil, mud

SECTION V – MEDICAL

SURVEILLANCE: Immunologic techniques being developed but reagents not widely available

FIRST AID/TREATMENT: Antibiotic therapy

IMMUNIZATION: None

PROPHYLAXIS: Penicillin

SECTION VI – LABORATORY HAZARDS

LABORATORY-ACQUIRED INFECTIONS: No reported cases of lab infection with Peptococcus spp.

SOURCES/SPECIMENS: Blood, feces, genital specimens, respiratory secretions, wound exudates

PRIMARY HAZARDS: Hazard of infection is low, however avoid accidental parenteral inoculation, ingestion, inhalation of infectious droplets

SPECIAL HAZARDS: None

SECTION VII – RECOMMENDED PRECAUTIONS

CONTAINMENT REQUIREMENTS: Well designed laboratory with good microbiological practices; this level of containment does not allow for any additional risk that may present for those persons with pre-existing disease, compromised immunity or who are pregnant

PROTECTIVE CLOTHING: Laboratory coat; gloves when contact with infectious materials in unavoidable

OTHER PRECAUTIONS: None

SECTION VIII – HANDLING INFORMATION

SPILLS: Allow aerosols to settle; wearing protective clothing, gently cover spill with absorbent paper towel and apply 1% sodium hypochlorite, starting at perimeter and working towards the centre; allow sufficient contact time (30 min) before clean up

DISPOSAL: Decontaminate before disposal; steam sterilization, chemical disinfection

STORAGE: In sealed containers that are appropriately labelled

SECTION IX – MISCELLANEOUS INFORMATION

Date prepared: September, 1996 Prepared by: Office of Biosafety

LCDC

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