Bluetongue Virus
Bluetongue Virus
MATERIAL SAFETY DATA SHEET – INFECTIOUS SUBSTANCES
SECTION I – INFECTIOUS AGENT
NAME: Bluetongue virus
SYNONYM OR CROSS REFERENCE: None
CHARACTERISTICS: Double capsid shell, naked, icosahedral virion; 60-80 nm diameter; segmented, linear, double-stranded RNA genome; Reoviridae; genus Orbivirus
SECTION II – HEALTH HAZARD
PATHOGENICITY: A non contagious, insect-transmitted, viral disease of sheep, cattle, goats, and wild ruminants
EPIDEMIOLOGY: The disease occurs widely on the African continent and to a lesser extent in North America, Asia, and Europe. In Canada, seroreactors are restricted to the Okanagan Valley
HOST RANGE: Sheep, cattle, goats and wild ruminants
INFECTIOUS DOSE: Not known
MODE OF TRANSMISSION: Non contagious; biologically transmitted by biting insects of the genus Culicoides
INCUBATION PERIOD: The usual incubation period in sheep is 5-10 days
COMMUNICABILITY: Non contagious
SECTION III – DISSEMINATION
RESERVOIR: Cattle and some wild ruminant species may act as reservoirs for sheep
ZOONOSIS: None
VECTORS: Biting insects of the genus Culicoides
SECTION IV – VIABILITY
DRUG SUSCEPTIBILITY: Not applicable
SUSCEPTIBILITY TO DISINFECTANTS: Susceptible to 95% ethanol, 2% formalin, 5% lysol, 2% sodium hypochlorite but requires prolonged exposure
PHYSICAL INACTIVATION: Stable at acidic pH (3.0-3.5), sensitive to heating above 50°C
SURVIVAL OUTSIDE HOST: Survives for months at 4°C and 20°C
SECTION V – MEDICAL
SURVEILLANCE: Not applicable
FIRST AID/TREATMENT: Not applicable
IMMUNIZATION: Not applicable
PROPHYLAXIS: Not applicable
SECTION VI – LABORATORY HAZARDS
LABORATORY-ACQUIRED INFECTIONS: None
SOURCES/SPECIMENS: Whole blood
PRIMARY HAZARDS: None
SPECIAL HAZARDS: None
SECTION VII – RECOMMENDED PRECAUTIONS
CONTAINMENT REQUIREMENTS: Bluetongue virus is considered to be not indigenous to Canada. Agriculture Canada will establish conditions under which the virus is used and maintained
PROTECTIVE CLOTHING: Solid front gown
OTHER PRECAUTIONS: None
SECTION VIII – HANDLING INFORMATION
SPILLS: Cover spill with absorbent paper towel and apply 2% sodium hypochlorite starting at the perimeter and working towards the centre; wait 30 min before clean up
DISPOSAL: Decontaminate all wastes before disposal; steam sterilization, chemical disinfection, incineration
STORAGE: Sealed containers, appropriately labelled
SECTION IX – MISCELLANEOUS INFORMATION
Date prepared: November 1999
Prepared by: Office of Laboratory Security, PHAC
Although the information, opinions and recommendations contained in this Material Safety Data Sheet are compiled from sources believed to be reliable, we accept no responsibility for the accuracy, sufficiency, or reliability or for any loss or injury resulting from the use of the information. Newly discovered hazards are frequent and this information may not be completely up to date.
Copyright © Health Canada, 2001
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